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MicroRNA-21 stimulates epithelial-to-mesenchymal transition and tumorigenesis in clear cell renal cells

Clear cell renal cell carcinoma (ccRCC) metastasis may result from epithelial-to-mesenchymal transition and mesenchymal stem cells that contribute to the development of the primary tumor. In this study, it was demonstrated that microRNA-21 (miR-21) acts as an oncogenic driver of ccRCC. ccRCC spheres...

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Detalles Bibliográficos
Autores principales: CAO, JIAN, LIU, JUN, XU, RAN, ZHU, XUAN, LIU, LEI, ZHAO, XIAOKUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686059/
https://www.ncbi.nlm.nih.gov/pubmed/26572589
http://dx.doi.org/10.3892/mmr.2015.4568