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Discovering Molecules That Regulate Efferocytosis Using Primary Human Macrophages and High Content Imaging

Defective clearance of apoptotic cells can result in sustained inflammation and subsequent autoimmunity. Macrophages, the “professional phagocyte” of the body, are responsible for efficient, non-phlogistic, apoptotic cell clearance. Controlling phagocytosis of apoptotic cells by macrophages is an at...

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Detalles Bibliográficos
Autores principales: Santulli-Marotto, Sandra, Gervais, Alexis, Fisher, Jamie, Strake, Brandy, Ogden, Carol Anne, Riveley, Chelsea, Giles-Komar, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686065/
https://www.ncbi.nlm.nih.gov/pubmed/26674639
http://dx.doi.org/10.1371/journal.pone.0145078