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Evaluation of the dynamic pattern of viral evolution in patients with virological breakthrough during treatment with nucleoside/nucleotide analogs by ultra-deep pyrosequencing

Virological breakthrough is a clinical manifestation in patients infected with chronic hepatitis B (CHB), who undergo treatment with nucleoside/nucleotide analogs (NUCs). The current understanding of the underlying mechanism of virological breakthrough is limited. Ultra-deep pyrosequencing (UDPS) is...

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Detalles Bibliográficos
Autores principales: CHEN, SHAOLONG, WU, JING, GU, ERLI, SHEN, YAOJIE, WANG, FEIFEI, ZHANG, WENHONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686096/
https://www.ncbi.nlm.nih.gov/pubmed/26648309
http://dx.doi.org/10.3892/mmr.2015.4577