Cargando…

Multi-transgenic minipig models exhibiting potential for hepatic insulin resistance and pancreatic apoptosis

There are currently no multi-transgenic minipig models of diabetes for the regulation of multiple genes involved in its pathogenesis. The foot and mouth disease virus 2A (F2A)-mediated polycistronic system possesses several advantages, and the present study developed a novel multi-transgenic minipig...

Descripción completa

Detalles Bibliográficos
Autores principales: KONG, SIYUAN, RUAN, JINXUE, XIN, LEILEI, FAN, JUNHUA, XIA, JIHAN, LIU, ZHIGUO, MU, YULIAN, YANG, SHULIN, LI, KUI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686100/
https://www.ncbi.nlm.nih.gov/pubmed/26648014
http://dx.doi.org/10.3892/mmr.2015.4582