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Metformin inhibits early stage diethylnitrosamine-induced hepatocarcinogenesis in rats

Antitumor effects of metformin have recently emerged despite its original use for type II diabetes. In the present study, the effects of metformin on the development and recurrence of hepatocellular carcinoma (HCC) were investigated using the diethylnitrosamine (DEN)-induced rat model of HCC. Tumor...

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Detalles Bibliográficos
Autores principales: JO, WOORI, YU, EUN-SIL, CHANG, MINSUN, PARK, HYUN-KYU, CHOI, HYUN-JI, RYU, JAE-EUN, JANG, SUNGWOONG, LEE, HYO-JU, JANG, JA-JUNE, SON, WOO-CHAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686101/
https://www.ncbi.nlm.nih.gov/pubmed/26548419
http://dx.doi.org/10.3892/mmr.2015.4513