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Metformin inhibits early stage diethylnitrosamine-induced hepatocarcinogenesis in rats
Antitumor effects of metformin have recently emerged despite its original use for type II diabetes. In the present study, the effects of metformin on the development and recurrence of hepatocellular carcinoma (HCC) were investigated using the diethylnitrosamine (DEN)-induced rat model of HCC. Tumor...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686101/ https://www.ncbi.nlm.nih.gov/pubmed/26548419 http://dx.doi.org/10.3892/mmr.2015.4513 |