Identification of the Novel TMEM16A Inhibitor Dehydroandrographolide and Its Anticancer Activity on SW620 Cells

TMEM16A, a calcium-activated chloride channel (CaCC), is highly amplified and expressed in human cancers and is involved in the growth and metastasis of some malignancies. Inhibition of TMEM16A represents a novel pharmaceutical approach for the treatment of cancers and metastases. The purpose of thi...

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Detalles Bibliográficos
Autores principales: Sui, Yujie, Wu, Fei, Lv, Junfeng, Li, Hongxia, Li, Xin, Du, Zhenwu, Sun, Meiyan, Zheng, Yuhao, Yang, Longfei, Zhong, Lili, Zhang, Xingyi, Zhang, Guizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686118/
https://www.ncbi.nlm.nih.gov/pubmed/26657333
http://dx.doi.org/10.1371/journal.pone.0144715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686118/
https://www.ncbi.nlm.nih.gov/pubmed/26657333
http://dx.doi.org/10.1371/journal.pone.0144715

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