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Intravital Imaging of Vascular Transmigration by the Lyme Spirochete: Requirement for the Integrin Binding Residues of the B. burgdorferi P66 Protein

Vascular extravasation, a key step in systemic infection by hematogenous microbial pathogens, is poorly understood, but has been postulated to encompass features similar to vascular transmigration by leukocytes. The Lyme disease spirochete can cause a variety of clinical manifestations, including ar...

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Detalles Bibliográficos
Autores principales: Kumar, Devender, Ristow, Laura C., Shi, Meiqing, Mukherjee, Priyanka, Caine, Jennifer A., Lee, Woo-Yong, Kubes, Paul, Coburn, Jenifer, Chaconas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686178/
https://www.ncbi.nlm.nih.gov/pubmed/26684456
http://dx.doi.org/10.1371/journal.ppat.1005333