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Binding of Cyclic Di-AMP to the Staphylococcus aureus Sensor Kinase KdpD Occurs via the Universal Stress Protein Domain and Downregulates the Expression of the Kdp Potassium Transporter

Nucleotide signaling molecules are important intracellular messengers that regulate a wide range of biological functions. The human pathogen Staphylococcus aureus produces the signaling nucleotide cyclic di-AMP (c-di-AMP). This molecule is common among Gram-positive bacteria and in many organisms is...

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Detalles Bibliográficos
Autores principales: Moscoso, Joana A., Schramke, Hannah, Zhang, Yong, Tosi, Tommaso, Dehbi, Amina, Jung, Kirsten, Gründling, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686210/
https://www.ncbi.nlm.nih.gov/pubmed/26195599
http://dx.doi.org/10.1128/JB.00480-15