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Autophagy facilitates lung adenocarcinoma resistance to cisplatin treatment by activation of AMPK/mTOR signaling pathway

Resistance to cisplatin-based therapy is a major challenge in the control of lung cancer progression. However, the underlying mechanisms remain largely unclear. Autophagy is closely associated with resistance to lung cancer therapy, but the function of autophagy in cisplatin treatment is still contr...

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Detalles Bibliográficos
Autores principales: Wu, Tao, Wang, Min-Cong, Jing, Li, Liu, Zhi-Yan, Guo, Hui, Liu, Ying, Bai, Yi-Yang, Cheng, Yang-Zi, Nan, Ke-Jun, Liang, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686226/
https://www.ncbi.nlm.nih.gov/pubmed/26715839
http://dx.doi.org/10.2147/DDDT.S95606