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Promoter methylation regulates cyclooxygenase expression in breast cancer

INTRODUCTION: Overexpression of cyclooxygenase (COX-2) is commonly observed in human cancers. In a murine model of metastatic breast cancer, we observed that COX-2 expression and enzyme activity were associated with enhanced tumorigenic and metastatic potential. In contrast to the high COX-2 express...

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Detalles Bibliográficos
Autores principales: Ma, Xinrong, Yang, Qingyuan, Wilson, Keith T, Kundu, Namita, Meltzer, Stephen J, Fulton, Amy M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC468630/
https://www.ncbi.nlm.nih.gov/pubmed/15217498
http://dx.doi.org/10.1186/bcr793