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Promoter methylation regulates cyclooxygenase expression in breast cancer
INTRODUCTION: Overexpression of cyclooxygenase (COX-2) is commonly observed in human cancers. In a murine model of metastatic breast cancer, we observed that COX-2 expression and enzyme activity were associated with enhanced tumorigenic and metastatic potential. In contrast to the high COX-2 express...
Autores principales: | Ma, Xinrong, Yang, Qingyuan, Wilson, Keith T, Kundu, Namita, Meltzer, Stephen J, Fulton, Amy M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC468630/ https://www.ncbi.nlm.nih.gov/pubmed/15217498 http://dx.doi.org/10.1186/bcr793 |
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