Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites

INTRODUCTION: Compromised patterns of gene expression result in genomic instability, altered patterns of gene expression and tumour formation. Specifically, aberrant DNA hypermethylation in gene promoter regions leads to gene silencing, whereas global hypomethylation events can result in chromosomal...

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Detalles Bibliográficos
Autores principales: Sadikovic, Bekim, Haines, Thomas R, Butcher, Darci T, Rodenhiser, David I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC468641/
https://www.ncbi.nlm.nih.gov/pubmed/15217500
http://dx.doi.org/10.1186/bcr799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC468641/
https://www.ncbi.nlm.nih.gov/pubmed/15217500
http://dx.doi.org/10.1186/bcr799

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