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Hypothesis: Induced angiogenesis after surgery in premenopausal node-positive breast cancer patients is a major underlying reason why adjuvant chemotherapy works particularly well for those patients

BACKGROUND: We suggest that surgical extirpation of primary breast cancer among other effects accelerates relapse for some premenopausal node-positive patients. These accelerated relapses occur within 10 months of surgery for untreated patients. The mechanism proposed is a stimulation of angiogenesi...

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Detalles Bibliográficos
Autores principales: Retsky, Michael, Bonadonna, Gianni, Demicheli, Romano, Folkman, Judah, Hrushesky, William, Valagussa, Pinuccia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC468653/
https://www.ncbi.nlm.nih.gov/pubmed/15217504
http://dx.doi.org/10.1186/bcr804