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In-Depth Characterization of Protein Disulfide Bonds by Online Liquid Chromatography-Electrochemistry-Mass Spectrometry

Disulfide bonds are an important class of protein post-translational modifications, yet this structurally crucial modification type is commonly overlooked in mass spectrometry (MS)-based proteomics approaches. Recently, the benefits of online electrochemistry-assisted reduction of protein S–S bonds...

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Detalles Bibliográficos
Autores principales: Switzar, Linda, Nicolardi, Simone, Rutten, Julie W., Oberstein, Saskia A. J. Lesnik, Aartsma-Rus, Annemieke, van der Burgt, Yuri E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686567/
https://www.ncbi.nlm.nih.gov/pubmed/26369777
http://dx.doi.org/10.1007/s13361-015-1258-z