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Auraptene consolidates memory, reverses scopolamine-disrupted memory in passive avoidance task, and ameliorates retention deficits in mice

OBJECTIVE(S): Auraptene (7-geranyloxycoumarin) (AUR), from Citrus species has shown anti-inflammatory, neuroprotective, and acetylcholinesterase (AChE) and beta-secretase inhibitory effects. Scopolamine is a nonselective muscarinic receptor antagonist which causes short-term memory impairments and i...

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Detalles Bibliográficos
Autores principales: Tabrizian, Kaveh, Yaghoobi, Najmeh Sadat, Iranshahi, Mehrdad, Shahraki, Jafar, Rezaee, Ramin, Hashemzaei, Mahmoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686572/
https://www.ncbi.nlm.nih.gov/pubmed/26730337