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The DNMT3B C→T promoter polymorphism and risk of breast cancer in a British population: a case-control study
BACKGROUND: Gene promoter methylation is an important regulator of expression and is a key epigenetic factor in tumorigenesis. DNA methylation is mediated by DNA methyltransferases (DNMTs), of which three active forms have been identified: DNMT1, DNM3A and DNMT3B. The C→T transition polymorphism (C4...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC468658/ https://www.ncbi.nlm.nih.gov/pubmed/15217506 http://dx.doi.org/10.1186/bcr807 |