Cargando…

The DNMT3B C→T promoter polymorphism and risk of breast cancer in a British population: a case-control study

BACKGROUND: Gene promoter methylation is an important regulator of expression and is a key epigenetic factor in tumorigenesis. DNA methylation is mediated by DNA methyltransferases (DNMTs), of which three active forms have been identified: DNMT1, DNM3A and DNMT3B. The C→T transition polymorphism (C4...

Descripción completa

Detalles Bibliográficos
Autores principales: Montgomery, Karen G, Liu, Mira CP, Eccles, Diana M, Campbell, Ian G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC468658/
https://www.ncbi.nlm.nih.gov/pubmed/15217506
http://dx.doi.org/10.1186/bcr807