SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment

Despite the recent evidence of the existence of myelodysplastic syndrome (MDS) stem cells in 5q-MDS patients, it is unclear whether haematopoietic stem cells (HSCs) could also be the initiating cells in other MDS subgroups. Here we demonstrate that SF3B1 mutation(s) in our cohort of MDS patients wit...

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Detalles Bibliográficos
Autores principales: Mian, Syed A., Rouault-Pierre, Kevin, Smith, Alexander E., Seidl, Thomas, Pizzitola, Irene, Kizilors, Aytug, Kulasekararaj, Austin G., Bonnet, Dominique, Mufti, Ghulam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686651/
https://www.ncbi.nlm.nih.gov/pubmed/26643973
http://dx.doi.org/10.1038/ncomms10004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686651/
https://www.ncbi.nlm.nih.gov/pubmed/26643973
http://dx.doi.org/10.1038/ncomms10004

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