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Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression
Changes in gene expression during tumorigenesis are often considered the consequence of de novo mutations occurring in the tumour. An alternative possibility is that the transcriptional response of oncogenic transcription factors evolves during tumorigenesis. Here we show that aberrant E2f activity,...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686657/ https://www.ncbi.nlm.nih.gov/pubmed/26639898 http://dx.doi.org/10.1038/ncomms10028 |