Cargando…

Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression

Changes in gene expression during tumorigenesis are often considered the consequence of de novo mutations occurring in the tumour. An alternative possibility is that the transcriptional response of oncogenic transcription factors evolves during tumorigenesis. Here we show that aberrant E2f activity,...

Descripción completa

Detalles Bibliográficos
Autores principales: Tarangelo, Amy, Lo, Nathanael, Teng, Rebecca, Kim, Eunsun, Le, Linh, Watson, Deborah, Furth, Emma E., Raman, Pichai, Ehmer, Ursula, Viatour, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686657/
https://www.ncbi.nlm.nih.gov/pubmed/26639898
http://dx.doi.org/10.1038/ncomms10028