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Expression of hypoxia-inducible factor-1α and cell cycle proteins in invasive breast cancer are estrogen receptor related

BACKGROUND: The transcription factor hypoxia-inducible factor-1 (HIF-1) is a key regulator of the cellular response to hypoxia. Previous studies showed that concentrations of its subunit HIF-1α, as a surrogate for HIF-1 activity, are increased during breast carcinogenesis and can independently predi...

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Detalles Bibliográficos
Autores principales: Bos, Reinhard, van Diest, Paul J, van der Groep, Petra, Shvarts, Avi, Greijer, Astrid E, van der Wall, Elsken
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC468666/
https://www.ncbi.nlm.nih.gov/pubmed/15217513
http://dx.doi.org/10.1186/bcr813