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Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics
Unculturable bacterial communities provide a rich source of biocatalysts, but their experimental discovery by functional metagenomics is difficult, because the odds are stacked against the experimentor. Here we demonstrate functional screening of a million-membered metagenomic library in microfluidi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686663/ https://www.ncbi.nlm.nih.gov/pubmed/26639611 http://dx.doi.org/10.1038/ncomms10008 |