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Asymmetric intramolecular α-cyclopropanation of aldehydes using a donor/acceptor carbene mimetic

Enantioselective α-alkylation of carbonyl is considered as one of the most important processes for asymmetric synthesis. Common alkylation agents, that is, alkyl halides, are notorious substrates for both Lewis acids and organocatalysts. Recently, olefins emerged as a benign alkylating species via p...

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Detalles Bibliográficos
Autores principales: Luo, Chaosheng, Wang, Zhen, Huang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686670/
https://www.ncbi.nlm.nih.gov/pubmed/26644194
http://dx.doi.org/10.1038/ncomms10041