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Asymmetric intramolecular α-cyclopropanation of aldehydes using a donor/acceptor carbene mimetic
Enantioselective α-alkylation of carbonyl is considered as one of the most important processes for asymmetric synthesis. Common alkylation agents, that is, alkyl halides, are notorious substrates for both Lewis acids and organocatalysts. Recently, olefins emerged as a benign alkylating species via p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686670/ https://www.ncbi.nlm.nih.gov/pubmed/26644194 http://dx.doi.org/10.1038/ncomms10041 |