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Adseverin mediates RANKL-induced osteoclastogenesis by regulating NFATc1

Adseverin is a Ca(2+)-dependent actin filament-severing protein that has been reported to regulate exocytosis via rearrangements of the actin cytoskeleton in secretory cells. However, the role of adseverin in bone cells has not yet been well characterized. Here, we investigated the role of adseverin...

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Detalles Bibliográficos
Autores principales: Song, Min-Kyoung, Lee, Zang Hee, Kim, Hong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686697/
https://www.ncbi.nlm.nih.gov/pubmed/26642432
http://dx.doi.org/10.1038/emm.2015.94