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Structural studies on molecular mechanisms of Nelfinavir resistance caused by non-active site mutation V77I in HIV-1 protease

BACKGROUND: The human immunodeficiency virus (HIV-1) is a retrovirus causing acquired immunodeficiency syndrome (AIDS), which has become a serious problem across the world and has no cure reported to date. Human immunodeficiency virus (HIV-1) protease is an attractive target for antiviral treatment...

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Detalles Bibliográficos
Autores principales: Gupta, Ankita, Jamal, Salma, Goyal, Sukriti, Jain, Ritu, Wahi, Divya, Grover, Abhinav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686784/
https://www.ncbi.nlm.nih.gov/pubmed/26695135
http://dx.doi.org/10.1186/1471-2105-16-S19-S10