Cargando…

NERI: network-medicine based integrative approach for disease gene prioritization by relative importance

BACKGROUND: Complex diseases are characterized as being polygenic and multifactorial, so this poses a challenge regarding the search for genes related to them. With the advent of high-throughput technologies for genome sequencing, gene expression measurements (transcriptome), and protein-protein int...

Descripción completa

Detalles Bibliográficos
Autores principales: Simões, Sérgio N, Martins, David C, Pereira, Carlos AB, Hashimoto, Ronaldo F, Brentani, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686785/
https://www.ncbi.nlm.nih.gov/pubmed/26696568
http://dx.doi.org/10.1186/1471-2105-16-S19-S9