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NERI: network-medicine based integrative approach for disease gene prioritization by relative importance
BACKGROUND: Complex diseases are characterized as being polygenic and multifactorial, so this poses a challenge regarding the search for genes related to them. With the advent of high-throughput technologies for genome sequencing, gene expression measurements (transcriptome), and protein-protein int...
Autores principales: | Simões, Sérgio N, Martins, David C, Pereira, Carlos AB, Hashimoto, Ronaldo F, Brentani, Helena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686785/ https://www.ncbi.nlm.nih.gov/pubmed/26696568 http://dx.doi.org/10.1186/1471-2105-16-S19-S9 |
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