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Prediction of tissue-specific effects of gene knockout on apoptosis in different anatomical structures of human brain

BACKGROUND: An important issue in the target identification for the drug design is the tissue-specific effect of inhibition of target genes. The task of assessing the tissue-specific effect in suppressing gene activity is especially relevant in the studies of the brain, because a significant variabi...

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Detalles Bibliográficos
Autores principales: Petrovskiy, Evgeny D, Saik, Olga V, Tiys, Evgeny S, Lavrik, Inna N, Kolchanov, Nikolay A, Ivanisenko, Vladimir A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686796/
https://www.ncbi.nlm.nih.gov/pubmed/26693857
http://dx.doi.org/10.1186/1471-2164-16-S13-S3