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Prediction of tissue-specific effects of gene knockout on apoptosis in different anatomical structures of human brain
BACKGROUND: An important issue in the target identification for the drug design is the tissue-specific effect of inhibition of target genes. The task of assessing the tissue-specific effect in suppressing gene activity is especially relevant in the studies of the brain, because a significant variabi...
Autores principales: | Petrovskiy, Evgeny D, Saik, Olga V, Tiys, Evgeny S, Lavrik, Inna N, Kolchanov, Nikolay A, Ivanisenko, Vladimir A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686796/ https://www.ncbi.nlm.nih.gov/pubmed/26693857 http://dx.doi.org/10.1186/1471-2164-16-S13-S3 |
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