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Rapid RNA–ligand interaction analysis through high-information content conformational and stability landscapes

The structure and biological properties of RNAs are a function of changing cellular conditions, but comprehensive, simultaneous investigation of the effect of multiple interacting environmental variables is not easily achieved. We have developed an efficient, high-throughput method to characterize R...

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Detalles Bibliográficos
Autores principales: Baird, Nathan J., Inglese, James, Ferré-D'Amaré, Adrian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686816/
https://www.ncbi.nlm.nih.gov/pubmed/26638992
http://dx.doi.org/10.1038/ncomms9898