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Rapid RNA–ligand interaction analysis through high-information content conformational and stability landscapes
The structure and biological properties of RNAs are a function of changing cellular conditions, but comprehensive, simultaneous investigation of the effect of multiple interacting environmental variables is not easily achieved. We have developed an efficient, high-throughput method to characterize R...
Autores principales: | Baird, Nathan J., Inglese, James, Ferré-D'Amaré, Adrian R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686816/ https://www.ncbi.nlm.nih.gov/pubmed/26638992 http://dx.doi.org/10.1038/ncomms9898 |
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