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A redox signalling globin is essential for reproduction in Caenorhabditis elegans

Moderate levels of reactive oxygen species (ROS) are now recognized as redox signalling molecules. However, thus far, only mitochondria and NADPH oxidases have been identified as cellular sources of ROS in signalling. Here we identify a globin (GLB-12) that produces superoxide, a type of ROS, which...

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Detalles Bibliográficos
Autores principales: De Henau, Sasha, Tilleman, Lesley, Vangheel, Matthew, Luyckx, Evi, Trashin, Stanislav, Pauwels, Martje, Germani, Francesca, Vlaeminck, Caroline, Vanfleteren, Jacques R., Bert, Wim, Pesce, Alessandra, Nardini, Marco, Bolognesi, Martino, De Wael, Karolien, Moens, Luc, Dewilde, Sylvia, Braeckman, Bart P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686822/
https://www.ncbi.nlm.nih.gov/pubmed/26621324
http://dx.doi.org/10.1038/ncomms9782