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CX3CR1 deficiency promotes muscle repair and regeneration by enhancing macrophage ApoE production

Muscle injury triggers inflammation in which infiltrating mononuclear phagocytes are crucial for tissue regeneration. The interaction of the CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axis that guides phagocyte infiltration is incompletely understood. Here, we show that CX3CR1 deficiency promotes muscle...

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Detalles Bibliográficos
Autores principales: Arnold, Ludovic, Perrin, Hélène, de Chanville, Camille Baudesson, Saclier, Marielle, Hermand, Patricia, Poupel, Lucie, Guyon, Elodie, Licata, Fabrice, Carpentier, Wassila, Vilar, José, Mounier, Rémi, Chazaud, Bénédicte, Benhabiles, Nora, Boissonnas, Alexandre, Combadiere, Béhazine, Combadiere, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686853/
https://www.ncbi.nlm.nih.gov/pubmed/26632270
http://dx.doi.org/10.1038/ncomms9972