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Developmental genes significantly afflicted by aberrant promoter methylation and somatic mutation predict overall survival of late-stage colorectal cancer

Carcinogenesis is an exceedingly complicated process, which involves multi-level dysregulations, including genomics (majorly caused by somatic mutation and copy number variation), DNA methylomics, and transcriptomics. Therefore, only looking into one molecular level of cancer is not sufficient to un...

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Detalles Bibliográficos
Autores principales: An, Ning, Yang, Xue, Cheng, Shujun, Wang, Guiqi, Zhang, Kaitai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686889/
https://www.ncbi.nlm.nih.gov/pubmed/26691761
http://dx.doi.org/10.1038/srep18616