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Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells

Reprogramming acinar cells into insulin producing cells using adenoviral (Ad)-mediated delivery of Pdx1, Ngn3 and MafA (PNM) is an innovative approach for the treatment of diabetes. Here, we aimed to investigate the molecular mechanisms involved in this process and in particular, the role of microRN...

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Detalles Bibliográficos
Autores principales: Teichenne, Joan, Morró, Meritxell, Casellas, Alba, Jimenez, Veronica, Tellez, Noelia, Leger, Adrien, Bosch, Fatima, Ayuso, Eduard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686894/
https://www.ncbi.nlm.nih.gov/pubmed/26690959
http://dx.doi.org/10.1371/journal.pone.0145116