ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity

Obesity is increasing in prevalence and is strongly associated with metabolic and cardiovascular disorders. The renin-angiotensin system (RAS) has emerged as a key pathogenic mechanism for these disorders; angiotensin (Ang)-converting enzyme 2 (ACE2) negatively regulates RAS by metabolizing Ang II i...

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Detalles Bibliográficos
Autores principales: Patel, Vaibhav B., Mori, Jun, McLean, Brent A., Basu, Ratnadeep, Das, Subhash K., Ramprasath, Tharmarajan, Parajuli, Nirmal, Penninger, Josef M., Grant, Maria B., Lopaschuk, Gary D., Oudit, Gavin Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686955/
https://www.ncbi.nlm.nih.gov/pubmed/26224885
http://dx.doi.org/10.2337/db15-0399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686955/
https://www.ncbi.nlm.nih.gov/pubmed/26224885
http://dx.doi.org/10.2337/db15-0399

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