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Competitive allele-specific TaqMan PCR (Cast-PCR) is a sensitive, specific and fast method for BRAF V600 mutation detection in Melanoma patients

BRAF codon 600 mutation testing of melanoma patients is mandatory for the choice of the most appropriate therapy in the clinical setting. Competitive allele specific TaqMan PCR (Cast-PCR) technology allows not only the selective amplification of minor alleles, but it also blocks the amplification of...

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Detalles Bibliográficos
Autores principales: Barbano, Raffaela, Pasculli, Barbara, Coco, Michelina, Fontana, Andrea, Copetti, Massimiliano, Rendina, Michelina, Valori, Vanna Maria, Graziano, Paolo, Maiello, Evaristo, Fazio, Vito Michele, Parrella, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686972/
https://www.ncbi.nlm.nih.gov/pubmed/26690267
http://dx.doi.org/10.1038/srep18592