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The Signal Transducer and Activator of Transcription 1 (STAT1) Inhibits Mitochondrial Biogenesis in Liver and Fatty Acid Oxidation in Adipocytes

The transcription factor STAT1 plays a central role in orchestrating responses to various pathogens by activating the transcription of nuclear-encoded genes that mediate the antiviral, the antigrowth, and immune surveillance effects of interferons and other cytokines. In addition to regulating gene...

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Detalles Bibliográficos
Autores principales: Sisler, Jennifer D., Morgan, Magdalena, Raje, Vidisha, Grande, Rebecca C., Derecka, Marta, Meier, Jeremy, Cantwell, Marc, Szczepanek, Karol, Korzun, William J., Lesnefsky, Edward J., Harris, Thurl E., Croniger, Colleen M., Larner, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4686975/
https://www.ncbi.nlm.nih.gov/pubmed/26689548
http://dx.doi.org/10.1371/journal.pone.0144444