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Molecular spectrum of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese colorectal cancer patients: analysis of 1,110 cases

Mutations in genes such as KRAS, NRAS, BRAF and PIK3CA have become an important part of colorectal carcinoma evaluation. The aim of this study was to screen for mutations in these genes in Chinese patients with colorectal cancer (CRC) and to explore their correlations with certain clinicopathologica...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Zheng, Jianming, Yang, Yinghong, Lu, Junliang, Gao, Jie, Lu, Tao, Sun, Jian, Jiang, Hui, Zhu, Yan, Zheng, Yuhui, Liang, Zhiyong, Liu, Tonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687048/
https://www.ncbi.nlm.nih.gov/pubmed/26691448
http://dx.doi.org/10.1038/srep18678