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Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases
Single-nucleotide polymorphisms within intron 1 of the FTO (fat mass and obesity-associated) gene are associated with enhanced FTO expression, increased body weight, obesity and type 2 diabetes mellitus (T2DM). The N(6)-methyladenosine (m(6)A) demethylase FTO plays a pivotal regulatory role for post...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687119/ https://www.ncbi.nlm.nih.gov/pubmed/26691922 http://dx.doi.org/10.1186/s12967-015-0746-z |