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Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases

Single-nucleotide polymorphisms within intron 1 of the FTO (fat mass and obesity-associated) gene are associated with enhanced FTO expression, increased body weight, obesity and type 2 diabetes mellitus (T2DM). The N(6)-methyladenosine (m(6)A) demethylase FTO plays a pivotal regulatory role for post...

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Detalles Bibliográficos
Autor principal:	Melnik, Bodo C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687119/ https://www.ncbi.nlm.nih.gov/pubmed/26691922 http://dx.doi.org/10.1186/s12967-015-0746-z

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