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Intravitreal Topotecan Inhibits Laser-induced Choroidal Neovascularization in a Rat Model
PURPOSE: A two-phase preclinical study was designed to determine the safe dose of intravitreal topotecan and its inhibitory effect on experimental choroidal neovascularization (CNV) in a rat model. METHODS: In phase I, 42 rats were categorized into 6 groups, 5 of which received intravitreal topoteca...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687264/ https://www.ncbi.nlm.nih.gov/pubmed/26730316 http://dx.doi.org/10.4103/2008-322X.170339 |