Monomethyl fumarate promotes Nrf2-dependent neuroprotection in retinal ischemia-reperfusion

BACKGROUND: Retinal ischemia results in neuronal degeneration and contributes to the pathogenesis of multiple blinding diseases. Recently, the fumaric acid ester dimethyl fumarate (DMF) has been FDA-approved for the treatment of multiple sclerosis, based on its neuroprotective and anti-inflammatory...

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, Hongkwan, Hartsock, Matthew J., Xu, Zhenhua, He, Meihua, Duh, Elia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687295/
https://www.ncbi.nlm.nih.gov/pubmed/26689280
http://dx.doi.org/10.1186/s12974-015-0452-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687295/
https://www.ncbi.nlm.nih.gov/pubmed/26689280
http://dx.doi.org/10.1186/s12974-015-0452-z

Ejemplares similares