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Monomethyl fumarate promotes Nrf2-dependent neuroprotection in retinal ischemia-reperfusion

BACKGROUND: Retinal ischemia results in neuronal degeneration and contributes to the pathogenesis of multiple blinding diseases. Recently, the fumaric acid ester dimethyl fumarate (DMF) has been FDA-approved for the treatment of multiple sclerosis, based on its neuroprotective and anti-inflammatory...

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Detalles Bibliográficos
Autores principales:	Cho, Hongkwan, Hartsock, Matthew J., Xu, Zhenhua, He, Meihua, Duh, Elia J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687295/ https://www.ncbi.nlm.nih.gov/pubmed/26689280 http://dx.doi.org/10.1186/s12974-015-0452-z

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