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Deficiency of myotubularin-related protein 14 influences body weight, metabolism, and inflammation in an age-dependent manner

BACKGROUND: Myotubularin-related protein 14 (MTMR14) is a novel phosphoinositide phosphatase with roles in the maintenance of normal muscle performance, autophagy, and aging in mice. Our initial pilot study demonstrated that MTMR14 knock out (KO) mice gain weight earlier than their wild-type (WT) li...

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Detalles Bibliográficos
Autores principales: Lv, Yin, Xue, Lu, Cai, Congli, Liu, Qing-Hua, Shen, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687302/
https://www.ncbi.nlm.nih.gov/pubmed/26697164
http://dx.doi.org/10.1186/s13578-015-0062-6