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PRX1 knockdown potentiates vitamin K3 toxicity in cancer cells: a potential new therapeutic perspective for an old drug
BACKGROUND: Many promising anticancer molecules are abandoned during the course from bench to bedside due to lack of clear-cut efficiency and/or severe side effects. Vitamin K3 (vitK3) is a synthetic naphthoquinone exhibiting significant in vitro and in vivo anticancer activity against multiple huma...
Autores principales: | He, Tiantian, Hatem, Elie, Vernis, Laurence, Lei, Ming, Huang, Meng-Er |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687332/ https://www.ncbi.nlm.nih.gov/pubmed/26689287 http://dx.doi.org/10.1186/s13046-015-0270-2 |
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