Inactivation of PI3-K/Akt and reduction of SP1 and p65 expression increase the effect of solamargine on suppressing EP4 expression in human lung cancer cells

BACKGROUND: Lung cancer is the most common cause of cancer-related deaths worldwide. Natural phytochemicals from traditional medicinal plants such as solamargine have been shown to have anticancer properties. The prostaglandin E2 receptor EP4 is highly expressed in human cancer, however, the functio...

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Detalles Bibliográficos
Autores principales: Chen, YuQing, Tang, Qing, Wu, JingJing, Zheng, Fang, Yang, LiJun, Hann, Swei Sunny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687355/
https://www.ncbi.nlm.nih.gov/pubmed/26689593
http://dx.doi.org/10.1186/s13046-015-0272-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687355/
https://www.ncbi.nlm.nih.gov/pubmed/26689593
http://dx.doi.org/10.1186/s13046-015-0272-0

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