Designing minimal microbial strains of desired functionality using a genetic algorithm

BACKGROUND: The rational, in silico prediction of gene-knockouts to turn organisms into efficient cell factories is an essential and computationally challenging task in metabolic engineering. Elementary flux mode analysis in combination with constraint minimal cut sets is a particularly powerful met...

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Detalles Bibliográficos
Autores principales: Nair, Govind, Jungreuthmayer, Christian, Hanscho, Michael, Zanghellini, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687386/
https://www.ncbi.nlm.nih.gov/pubmed/26697103
http://dx.doi.org/10.1186/s13015-015-0060-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687386/
https://www.ncbi.nlm.nih.gov/pubmed/26697103
http://dx.doi.org/10.1186/s13015-015-0060-6

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