Dysregulation of the haem-haemopexin axis is associated with severe malaria in a case–control study of Ugandan children

BACKGROUND: Malaria is associated with haemolysis and the release of plasma haem. Plasma haem can cause endothelial injury and organ dysfunction, and is normally scavenged by haemopexin to limit toxicity. It was hypothesized that dysregulation of the haem-haemopexin pathway contributes to severe and...

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Detalles Bibliográficos
Autores principales: Elphinstone, Robyn E., Riley, Frank, Lin, Tian, Higgins, Sarah, Dhabangi, Aggrey, Musoke, Charles, Cserti-Gazdewich, Christine, Regan, Raymond F., Warren, H. Shaw, Kain, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687388/
https://www.ncbi.nlm.nih.gov/pubmed/26691827
http://dx.doi.org/10.1186/s12936-015-1028-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687388/
https://www.ncbi.nlm.nih.gov/pubmed/26691827
http://dx.doi.org/10.1186/s12936-015-1028-1

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