Immunosuppressant MPA Modulates Tight Junction through Epigenetic Activation of MLCK/MLC-2 Pathway via p38MAPK

Background: Mycophenolic acid (MPA) is an important immunosuppressive drug (ISD) prescribed to prevent graft rejection in the organ transplanted patients, however, its use is also associated with adverse side effects like sporadic gastrointestinal (GI) disturbances. Recently, we reported the MPA ind...

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Detalles Bibliográficos
Autores principales: Khan, Niamat, Pantakani, D. V. Krishna, Binder, Lutz, Qasim, Muhammad, Asif, Abdul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687409/
https://www.ncbi.nlm.nih.gov/pubmed/26733876
http://dx.doi.org/10.3389/fphys.2015.00381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687409/
https://www.ncbi.nlm.nih.gov/pubmed/26733876
http://dx.doi.org/10.3389/fphys.2015.00381

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