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A conformational RNA zipper promotes intron ejection during non‐conventional XBP1 mRNA splicing

The kinase/endonuclease IRE1 is the most conserved signal transducer of the unfolded protein response (UPR), an intracellular signaling network that monitors and regulates the protein folding capacity of the endoplasmic reticulum (ER). Upon sensing protein folding perturbations in the ER, IRE1 initi...

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Detalles Bibliográficos
Autores principales: Peschek, Jirka, Acosta‐Alvear, Diego, Mendez, Aaron S, Walter, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687415/
https://www.ncbi.nlm.nih.gov/pubmed/26483401
http://dx.doi.org/10.15252/embr.201540955