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The Paf1 complex factors Leo1 and Paf1 promote local histone turnover to modulate chromatin states in fission yeast

The maintenance of open and repressed chromatin states is crucial for the regulation of gene expression. To study the genes involved in maintaining chromatin states, we generated a random mutant library in Schizosaccharomyces pombe and monitored the silencing of reporter genes inserted into the euch...

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Detalles Bibliográficos
Autores principales: Sadeghi, Laia, Prasad, Punit, Ekwall, Karl, Cohen, Amikam, Svensson, J Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687421/
https://www.ncbi.nlm.nih.gov/pubmed/26518661
http://dx.doi.org/10.15252/embr.201541214